VThunter
a database for single-cell screening of virus target cells in animal kingdom
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Chicken

Scientific Name: Gallus gallus

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Sauropsida-> Sauria-> Archelosauria-> Archosauria-> Dinosauria-> Saurischia-> Theropoda-> Coelurosauria-> Aves-> Neognathae-> Galloanserae-> Galliformes-> Phasianidae-> Phasianinae-> Gallus

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Enterovirus A71

Family: Picornaviridae

Receptor: SCARB2

Receptor SCARB2 information

Summary: The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011] [NCBI]  [Proteinatlas]

Data Source

Data set information

Project Date Technology Tissue Condition Cell PMID/DOI
Vthunter_1025 2018.07 Fluidigm C1 PrimitiveStreak Normal 175 Link
Vthunter_1006 2017.12 SMART-seq AnteriorNeuralTube Normal 500 Link
Vthunter_110067 2019.12 MARS-seq TotalBrain Normal 768 Link
Featureplot of receptors

Featureplot of receptors

mRNA expression of SCARB2 in human tissues   [NCBI]

Expression: Ubiquitous expression in brain (RPKM 74.6), prostate (RPKM 71.6) and 25 other tissues

Protein expression of SCARB2 in human tissues   [Proteinatlas]